Analysis of Gastrointestinal and Hepatobiliary Disorders



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Analysis of Gastrointestinal and Hepatobiliary Disorders













Analysis of Gastrointestinal and Hepatobiliary Disorders

My patient diagnosis for the symptoms presented of nausea, diarrhea, and vomiting is a presence of gastrointestinal disorder, a PUD (Peptic Ulcer Disease). The disease causes sore in the inner lining of the stomach and the intestines. Therefore, the gastric acid produced by the pancreas corrodes the walls, causing symptoms of nausea and vomit. Besides, because the condition is non-specific in its manifestations, the presented symptoms such as diarrhea, vomiting, and nausea are acute non-specific symptoms of this disease (Elliot et al., 2018). Similarly, based on the patient’s medical history, the case represents a situation of substance abuse and the possibility of Hepatitis C infection. These further intensify the symptoms presented on the patient (Robin et al., 2018). 

The effect of the drug prednisone on the gastrointestinal tract has been determined and found to elevate gastric acid production. According to various studies, a patient who uses this drug to manage some illnesses in their body presents this kind of symptom (Su et al., 2020). It has been determined that the drug causes duodenal ulcers and should stop its therapy on this patient. Besides, providing mucosal protection mechanisms such as sucralfate or subsalicylate can eliminate the effects of prednisone in the gastrointestinal system. According to the medical history of hepatitis C, the patient used prednisone medication to manage this condition. Hence the use should be stopped and replaced with Sovaldi (Sofosbuvir) 400mg tablet taken daily. 

Similarly, the patient should stop using Synthroid 100 mcg daily to manage this condition. One of the side effects of this drug is diarrhea, vomiting, and other intestinal abnormalities. Nifedipine 30mg daily should also be stopped and substituted by Nisoldipine 20 mg daily. Nifedipine also causes stomach upsets and heartburn; thus, its use is not necessary in this case. The protective measure reduces the possible corrosion of the surface caused by the production and activities of gastric acid by coasting the affected areas (Su et al., 2020).

For this reason, the patient’s case requires the incorporation of bismuth subsalicylate, 525mg hourly, for two days since if the drug is prolonged, side effects such as abdominal pain may occur(O’Malley, 2020). Besides, the drug should not be taken more than eight times a day. The drug will enhance mucus secretion, which protects the walls from corrosion by gastric acid. Similarly, the patient is advised on a good diet while under prednisone medication besides avoidance of drug and alcohol abuses.  This will prevent the patient from getting predisposed to gastritis or other life-threatening disorders.










Elliot, S. Y., SS, Y. P., & Venkatesan, T. (2018). Migraine, cyclic vomiting syndrome, and other gastrointestinal disorders. Current treatment options in gastroenterology16(4), 511-527. 

O’Malley, P. A. (2020). Pink Prescribing: Bismuth Subsalicylate; History, Actions, Risks, and Future Use. Clinical Nurse Specialist34(2), 45-47.

Robin, S. G., Keller, C., Zwiener, R., Hyman, P. E., Nurko, S., Saps, M., … & van Tilburg, M. A. (2018). Prevalence of pediatric functional gastrointestinal disorders utilizing the Rome IV criteriaThe Journal of pediatrics195, 134-139. 

Su, G. L., Ko, C. W., Bercik, P., Falck-Ytter, Y., Sultan, S., Weizman, A. V., & Morgan, R. L. (2020). AGA clinical practice guidelines on the role of probiotics in the management of gastrointestinal disorders. Gastroenterology159(2), 697-705.


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